Experts Predict Mesothelioma Epidemic in India

Once prized as an insulator and building material, the mineral asbestos is now recognized by health experts around the world, including the World Health Organization (WHO), as a potent carcinogen that can cause mesothelioma and other asbestos related diseases.  While many industrialized nations now ban or seriously restrict its use, India continues to import and use asbestos at a rate that is alarming the world medical community.

 

A recent article published in the British medical journal, The Lancet, predicts that with “India’s surging consumption of asbestos, the industry’s hefty political and economic clout, and the country’s poor record of worker protection….a sizeable burden of asbestos-related disease is inevitable” leading to health consequences that “will be felt into the next century.”  These health consequences could include an epidemic of mesothelioma.

A total of forty countries have now banned chrysotile (white) asbestos, the most common form of the mineral.  (The U.S. is not one of them.)  But between 2000 and 2007, India’s importation of asbestos rose from 125,000 metric tons to about 300,000, with most of it coming from Canada.  The asbestos is primarily mixed into cement and used in all types of building applications, including the production of cement roofing tiles, making them durable, sturdy and fireproof, unlike traditional thatched roof.  Since 1960, India has imported about 7 million metric tons of asbestos.

According to the World Health Organization, at least 90 thousand people die annually worldwide from asbestos-related lung cancer, asbestosis or mesothelioma.  Because mesothelioma can take 30 to 50 years after exposure to develop, the number of people contracting the disease continues to rise even in countries where it has been banned.  Because India does not track its cancer cases, it is difficult to get an estimate of the asbestos-related disease problem there. Experts suggest that many cases diagnosed as bronchitis or tuberculosis may actually be an unrecognized asbestos related illnesses.

In an editorial in the UK’s online magazine The Tribune, photojournalist Neil Hodge claims to have photographed Indian children making statues with sacks of asbestos cement, unprotected and unaware of the health risks.  Hodge says an Indian television channel even reported in 2007 that asbestos was being used in parts of the country to bleach rice to make it more attractive to consumers.  According to the Indian Health officials quoted in the article, most Indian consumers do not believe that asbestos is toxic, that it can cause cancer like mesothelioma, and there is little or no enforcement of safety legislation designed to protect workers.

Speaking in The Lancet, Drexel University professor and Chair of the Department of Environmental and Occupational Health, Arthur Frank, MD, PhD, warns, “We can expect a lot more death and disease [in India]. There is no champion for the working person, or for the elimination or reduction in the use of asbestos that I can see in the central Indian Government.”

Source:
  Mesothelioma

Cold Plasma Appears to Improve Mesothelioma Treatment

Adding a technique called Cold Plasma Coagulation to the mix when using surgery and intra-operative chemotherapy seems to help protect mesothelioma patients against certain complications, according to a new study.

 

Mesothelioma, a malignancy that affects the linings around the lungs and internal organs, is caused by asbestos exposure and is notoriously difficult to treat.  Depending on the stage of their cancer and their health status, most patients receive a combination of treatments which may include chemotherapy, radiation, radical surgery (Extrapleural pneumonectomy or EPP), or pleurectomy and decortication (P/D), a less radical surgical approach.  Even with these various combinations, many patients succumb to the disease within 18 months of diagnosis.

In an effort to improve mesothelioma survival rates, surgeons in recent years have begun combining pleurectomy and decortication with heated chemotherapy (hyperthermic intrathoracic chemoperfusion or HITHOC) that is washed through the effected body cavity during surgery.  While results of this combination therapy have been promising, there is the potential for damaging the pericardium (lining around the heart) or the diaphragm, leading to heart damage or the accidental spread of cancer cells into the abdomen.  

Now, researchers in Germany believe they have found a way to protect the pericardium and the diaphragm during P/D, while still allowing mesothelioma patients to benefit from the surgery and the HITHOC treatment.  In the study, Cold Plasma Coagulation (CPC) was used to destroy tumor cells on the pleura, diaphragm and pericardium before HITHOC was administered.  

Patients in the study all had Stage III pleural mesothelioma.  None of them suffered any cardiotoxic effects as the result of their treatment and none had had a recurrence of their cancer one year after surgery.  The researchers concluded that Cold Plasma Coagulation was a safe and potentially beneficial addition to a multimodal treatment approach for mesothelioma patients. 

In their abstract, the authors noted that the number of cases of mesothelioma continues to rise and is not expected reach its peak until 2015.  They caution, “We consider our trial as a pilot study. To evaluate potential survival benefits using this [Cold Plasma] technique, larger trials are mandatory.” 

The study titled “Cold-Plasma Coagulation in the Treatment of Malignant Pleural Mesothelioma: Results of a Combined Approach”, was published in the online journal Interactive Cardiovascular and Thoracic Surgery.

Sources: 

  Mesothelioma News

Cold Plasma Appears to Improve Mesothelioma Treatment

Adding a technique called Cold Plasma Coagulation to the mix when using surgery and intra-operative chemotherapy seems to help protect mesothelioma patients against certain complications, according to a new study.

 

Mesothelioma, a malignancy that affects the linings around the lungs and internal organs, is caused by asbestos exposure and is notoriously difficult to treat.  Depending on the stage of their cancer and their health status, most patients receive a combination of treatments which may include chemotherapy, radiation, radical surgery (Extrapleural pneumonectomy or EPP), or pleurectomy and decortication (P/D), a less radical surgical approach.  Even with these various combinations, many patients succumb to the disease within 18 months of diagnosis.

In an effort to improve mesothelioma survival rates, surgeons in recent years have begun combining pleurectomy and decortication with heated chemotherapy (hyperthermic intrathoracic chemoperfusion or HITHOC) that is washed through the effected body cavity during surgery.  While results of this combination therapy have been promising, there is the potential for damaging the pericardium (lining around the heart) or the diaphragm, leading to heart damage or the accidental spread of cancer cells into the abdomen.  

Now, researchers in Germany believe they have found a way to protect the pericardium and the diaphragm during P/D, while still allowing mesothelioma patients to benefit from the surgery and the HITHOC treatment.  In the study, Cold Plasma Coagulation (CPC) was used to destroy tumor cells on the pleura, diaphragm and pericardium before HITHOC was administered.  

Patients in the study all had Stage III pleural mesothelioma.  None of them suffered any cardiotoxic effects as the result of their treatment and none had had a recurrence of their cancer one year after surgery.  The researchers concluded that Cold Plasma Coagulation was a safe and potentially beneficial addition to a multimodal treatment approach for mesothelioma patients. 

In their abstract, the authors noted that the number of cases of mesothelioma continues to rise and is not expected reach its peak until 2015.  They caution, “We consider our trial as a pilot study. To evaluate potential survival benefits using this [Cold Plasma] technique, larger trials are mandatory.”  

The study titled “Cold-Plasma Coagulation in the Treatment of Malignant Pleural Mesothelioma: Results of a Combined Approach”, was published in the online journal Interactive Cardiovascular and Thoracic Surgery. 

Source:
  Mesothelioma